Taking Herbs with Hormonal Drug?

I was put on Prempro and was wondering if i can still take saw palmetto and damiana and ginseng.

If you have not done so already, I suggest that you do some internet research on Prempro to ensure that you are aware of the possible side effects.
I can't advise you on taking herbs with this drug without understanding your need for the herbs. The drug will control your hormones, so if you were taking the herbs for their hormonal actions, they will have no effect when you are taking the drug.