Problems with Herbal Combinations?

Is there a problem in taking shark cartillage, grape seed, milk thistle, black cohosh, and dandelion together daily?

I don't know of a particular problem with this combination. I can't say whether this combination will help you, though. All herbs have specific indications for use. Single herbs and combinations of herbs are recommended by herbalists and natural practitioners, specifically for an individual, after assessing the person's health. They are used for short periods of time while an underlying health condition is being worked on.