Kava Kava, Hops, Skullcap and Valerian

Could you please tell me if it is safe to mix kava with hops, skullcap, and valerian?

Yes, it is safe to mix these herbs, but you will have to monitor closely the effects of this relaxing and sedating combination. In calculating the dosage of this mixture, you should use only one quarter of the daily dosage of each herb. High doses of sedative constituents may cause extreme drowsiness or conversely may cause giddiness.
Hops should not be used in depression as it will lower the mood in a person whose mood is already low.